Haemotropic Mycoplasmas (Haemoplasmas): A Review

Authors

  • Fatemeh Mohammadkhan Department of Food Hygiene, Faculty of Veterinary Medicine, University of Tehran, Iran
  • Seyed Milad Vahedi Department of Internal Medicine, Faculty of Veterinary Medicine, University of Tehran, Iran
Abstract:

Haemoplasmas contain Eperythrozoon and Haemobartonella species, which are widespread causes of animal and human infections. These obligatory cell parasites were previously known as Hemobartonella; now hemotropic mycoplasmas. These bacteria are identified by the lack of cell wall and their small genome. The usual diameter is between 0.3 and1μm. Mycoplasmasarepolymorphic and seen in circular or bar shape, which aggregate and form pinion teeth on the surface of RBCs. Despite the small genome of mycoplasmas, the GC content is 23 to 40%.The genome contains a circular double stranded DNA. Mycoplasmas are notable to grow on culture media. Animals are usually infected with the hidden form of the disease and hence become carriers and sources for the spread of the infection. Since these bacteria are difficult to grow, the common methods of diagnosis are cytology and microscopic examinations. Today, the most reliable and definitive method for the detection of haemoplasmas polymerase chain reaction (PCR).The most important way for the transmission of bacteria is the insect bite including ticks. High density of hemotropic mycoplasmas causes RBC hemolysis and hence many symptoms including jaundice, lethargy, anemia, fever and acidosis. Mycoplasmas respond to antibiotic therapy. Effective antibiotics are available such as lincomycin, enrofloxacin, oxytetracycline and doxycycline. Hemoplasmas cause a wide range of diseases and play the role of a cofactor in many viral and neoplastic diseases. These diseases are common in many countries, including Iran.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

haemotropic mycoplasmas (haemoplasmas): a review

haemoplasmas contain eperythrozoon and haemobartonella species, which are widespread causes of animal and human infections. these obligatory cell parasites were previously known as hemobartonella; now hemotropic mycoplasmas. these bacteria are identified by the lack of cell wall and their small genome. the usual diameter is between 0.3 and1μm. mycoplasmasarepolymorphic and seen in circular or b...

full text

The role of mycoplasmas in non-gonococcal urethritis: a review.

The criteria that need to be fulfilled before regarding a mycoplasma as a cause of non-gonococcal urethritis (NGU) are outlined. Of the seven mycoplasmas that have been isolated from the human genitourinary tract, most cannot be considered as contenders for causing NGU. Although there is no evidence to support an etiological role for Mycoplasma hominis, it may be unwise to ignore this mycoplasm...

full text

Non-ribosomal phylogenetic exploration of Mollicute species: New insights into haemoplasma taxonomy

Nine species of uncultivable haemoplasmas and several Mycoplasma species were examined by partial sequencing of two protein-encoding housekeeping genes. Partial glyceraldehyde-3-phosphate dehydrogenase (gapA) and heat shock protein 70 (dnaK) gene sequences were determined for these Mollicute species; in total nine gapA sequences and ten dnaK sequences were obtained. Phylogenetic analyses of the...

full text

Origins of the mycoplasmas: sterol-nonrequiring mycoplasmas evolved from streptococci.

We report the establishment of a phylogenetic relationship between the sterol-nonrequiring mycoplasmas (Acholeplasma species) and streptococci. Three specific antisera prepared against purified Streptococcus faecalis fructose diphosphate aldolase and glyceraldehyde-3-phosphate dehydrogenase and Pediococcus cerevisiae glyceraldehyde-3-phosphate dehydrogenase were used for comparative enzyme immu...

full text

Mycoplasmas as pathogens.

This paper concerns several animal models for study of pathogenic mechanisms in mycoplasma infection. Although these will seem remote from the general topic of this symposium, it is conceivable that some of the mechanisms may have implications for chronic pulmonary disease. Mycoplasmas are known to be causative agents in acute and chronic pulmonary infections in several species of domestic anim...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 2  issue 5

pages  1484- 1503

publication date 2014-05-01

By following a journal you will be notified via email when a new issue of this journal is published.

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023